货号:STA-321 | 规格:100 assays | 目录价:¥9982.5 |
产品详情
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产品名称:
OxiSelect™ DNA Double-Strand Break (DSB) Staining Kit
产品描述:
Double-strand breaks (DSB) in DNA are among the most dangerous types of DNA damage occuring within cells. One of the earliest cellular responses to double-strand breaks is the phosphorylation of a histone variant, H2AX, at the sites of DNA damage. Within seconds Ser139 is phosphorylated when DSBs are induced in mammalian cells. Phosphorylation of this serine residue causes chromatin condensation and appears to play a critical role in the recruitment of repair or damage-signaling factors to the DNA damage sites. The OxiSelect™ DNA Double-Strand Break Staining Kit provides an easy-to-use method for detecting the presence of DSBs in cells cultured in microtiter plates. Double strand breaks can be detected in just a few hours by immunofluorescence staining of the phosphorylated histone H2AX.
保存温度:
-20ºC
运输温度:
Blue Ice
产地:
美国
生产商:
cell biolabs
检测方法:
Immunofluorescence
上一个:OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size
下一个:OxiSelect™ DNA Double Strand Break (DSB) Staining Kit, Trial Size
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