| 货号:26113-1 mg | 规格:1 mg | 目录价:¥2948 |
| 货号:26113-10 mg | 规格:10 mg | 目录价:¥13936 |
| 货号:26113-5 mg | 规格:5 mg | 目录价:¥8522 |
| 货号:26113-500 µg | 规格:500 µg | 目录价:¥1554 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
P053
产品描述:
An inhibitor of CerS1 (IC50s = 0.54 and 0.46 µM for human and mouse CerS1, respectively); selective for CerS1 over CerS2, CerS4, CerS5, and CerS6 (IC50s = 28.6, 17.2, 7.2, and 11.4 µM, respectively); lowers levels of C18 ceramide, C18 galactosylceramide, and C18:0 and 18:1 sphingomyelin species in HEK293 cells at 30-300 nM; decreases endogenous C18:1/18:0 and C18:2/18:0 ceramide levels in mouse skeletal muscle at 5 mg/kg; increases fatty acid oxidation in mouse skeletal muscle and inhibits triglyceride synthesis and increases in white adipose mass in a model of high-fat diet-induced obesity but does not affect insulin resistance
保存温度:
-20
运输温度:
-20
预期分子量:
354.27028
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
2748196-63-4
分子式:
C18H21Cl2NO2
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