| 货号:21229-1 mg | 规格:1 mg | 目录价:¥657 |
| 货号:21229-10 mg | 规格:10 mg | 目录价:¥3162 |
| 货号:21229-5 mg | 规格:5 mg | 目录价:¥1742 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
p38 MAPK Inhibitor VIII
别名:
EO 1428|p38 MAP Kinase Inhibitor VIII|p38 Mitogen-activated Protein Kinase Inhibitor VIII
产品描述:
An inhibitor of p38α (IC50 = 39 nM) and p38β MAP kinases with 82 and 93% inhibition, respectively, in a kinase assay (1 µM); selective for p38α and 38β, lacking activity at p38γ, p38δ, ERK1/2, and JNK1 at 1 µM; inhibits IL-1β, TNF-α, IL-6, IL-8, and IL-10, but not IFN-γ release from human peripheral blood mononuclear cells (IC50s = 30, 5, 17, 4, 10, and >1,000 nM, respectively); decreases ear swelling in mouse models of allergic and chronic irritative contact dermatitis (0.5 mg/ear, topical)
保存温度:
-20
运输温度:
-20
预期分子量:
415.7
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
321351-00-2
分子式:
C20H16BrClN2O
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