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折扣/货期| 货号：3073-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：3073-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PAK6 Antibody
别名:
PAK6 Antibody: PAK5, PAK5, PAK-5, PAK-6
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA,WB,ICC,IF
靶标/特异性:
PAK6 antibody is predicted to not cross-react with other PAK family proteins.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
PAK6 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
PAK6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PAK6 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
PAK6 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.
Accession #:
NP_064553
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