| 货号:23460-1 mg | 规格:1 mg | 目录价:¥1621 |
| 货号:23460-10 mg | 规格:10 mg | 目录价:¥12743 |
| 货号:23460-5 mg | 规格:5 mg | 目录价:¥6767 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Palosuran
别名:
ACT058362
产品描述:
An antagonist of UTR (IC50s = 3.6 and 1,475 nM for CHO cell membranes expressing human and rat recombinant receptors, respectively); inhibits urotensin II-induced contraction of isolated rat aortic rings in a concentration-dependent manner; reduces plasma endothelin-1, urotensin II, and TGF-β1 levels, as well the main pulmonary arterial pressure and right ventricular hypertrophy index in a monocrotaline-induced rat model of PAH at 300 mg/kg twice per day; reduces serum glucose, cholesterol, and triglyceride levels and increases survival in an STZ-induced rat model of diabetes at 300 mg/kg per day; decreases albuminuria and global kidney lesion scores in STZ-induced diabetic rats
保存温度:
-20
运输温度:
-20
预期分子量:
418.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
540769-28-6
分子式:
C25H30N4O2
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