深圳欣博盛生物科技有限公司 a1

PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)
货号:39109-1 g 规格:1 g 目录价:¥8937.8
货号:39109-500 mg 规格:500 mg 目录价:¥4703.4
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)
别名:
PAMAM G4.5 Carboxylate|Polyamidoamine Dendrimer G4.5 Carboxylate
产品描述:
A carboxylate-terminated PAMAM dendrimer; has been used in a drug delivery system; ~87.9 in diameter in water and has 96 surface groups; Unlike PAMAM G5.0, it does not rupture bilayer lipid membranes at 50 µM; PAMAM G4.5 carboxylate disulfur-linked aggregates encapsulating ferulic acid and paclitaxel induce apoptosis and decrease the mitochondrial membrane potential in multidrug-resistant KB-8-5 cancer cells at 10 µg/ml; complexes of PAMAM G4.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 cancer cells (IC50 = 620 nM); a fluorescently labeled form of PAMAM G4.5 carboxylate selectively accumulates in tumors and kidneys over liver, spleen, heart, and lungs in a 4T1 murine mammary carcinoma model
保存温度:
-20
运输温度:
-20
预期分子量:
23309.2
产品形式:
A solution in water
CAS号:
202009-66-3
分子式:
[NH2(CH2)2NH2]:(G=4.5);dendri PAMAM(NHCH2CH2COONa)128
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