深圳欣博盛生物科技有限公司 a1

PBI-4050 (sodium salt)
货号:42912-10 mg 规格:10 mg 目录价:¥2626
货号:42912-25 mg 规格:25 mg 目录价:¥4757
货号:42912-5 mg 规格:5 mg 目录价:¥1461
货号:42912-50 mg 规格:50 mg 目录价:¥7303
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PBI-4050 (sodium salt)
产品描述:
A FFAR/GPR40 agonist and GPR84 antagonist; induces β-arrestin-2 recruitment in a reporter assay using HEK293 cells expressing human FFAR1/GPR40 (EC50 = 275 µM); inhibits decanoic acid- or embelin-induced activation of GPR84 in reporter assays using HEK293 cells expressing the human receptor (IC50s = 398 and 209 µM, respectively); decreases renal histological lesion scores in a mouse model of doxorubicin-induced nephrotoxicity at 200 mg/kg; reduces tissue fibrosis in several additional in vivo rodent models, including carbon tetrachloride-induced hepatotoxicity and bleomycin-induced pulmonary fibrosis; decreases albuminuria, prevents decreases in GFR and podocyte numbers, and reduces blood glucose levels in a model of accelerated type 2 diabetes using eNos-/- db/db mice at 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
206.285
产品形式:
A solid
纯度:
≥98%
分子式:
C13H18O2 • Na
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询