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折扣/货期| 货号：29036-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：29036-10 mg | 规格：10 mg | 目录价：￥3390 |
| 货号：29036-25 mg | 规格：25 mg | 目录价：￥7866 |
| 货号：29036-5 mg | 规格：5 mg | 目录价：￥2050 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PCI-29732
产品描述:
A multi-kinase inhibitor; inhibits BTK, LCK, and LYN (Kis = 8.2, 4.6, and 2.5 nM, respectively), as well as the activity of three receptor tyrosine kinases and seven non-receptor tyrosine kinases by greater than 90% in a panel of over 100 kinases at 10 µM; inhibits calcium flux in Ramos B cells and phosphorylation of PLCɣ1 (IC50s = 0.53 and 0.33 µM, respectively); cytotoxic to S1-MI-80, H460/MX20, and KBv200 cancer cells overexpressing the ATP-binding cassette transporter (IC50s = 7.8, 6.3, and 6.02 µM, respectively); in combination with topotecan, reduces tumor growth in an H460/MX20 mouse xenograft model at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
371.43524
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
330786-25-9
分子式:
C22H21N5O
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