PD-1-IN-1-抑制剂-深圳欣博盛生物科技有限公司

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PD-1-IN-1

品牌：Cayman

官网链接

说明书

折扣/货期

货号：27775-1 mg	规格：1 mg	目录价：￥964.8
货号：27775-10 mg	规格：10 mg	目录价：￥7664.8
货号：27775-25 mg	规格：25 mg	目录价：￥14378.2
货号：27775-5 mg	规格：5 mg	目录价：￥4328.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PD-1-IN-1

别名:

CA-170|PD-1 Inhibitor 1|Programmed Cell Death 1 Inhibitor 1|Programmed Cell Death 1-IN-1

产品描述:

A PD-L1, PD-L2, and VISTA inhibitor; rescues PD-L1-, PD-L2-, or VISTA-induced inhibition of IFN-γ release in isolated human PBMCs stimulated with anti-CD3 and anti-CD28 antibodies (EC50s = 66.1, 80.9, and 82.9 nM, respectively); selective for these immune checkpoint proteins over B7-1 and CTLA-4 at 1,000 nM and a panel of 80 receptors, transporters, and enzymes at 10,000 nM; does not induce IL-2, IFN-γ, or TNF-α release in isolated human PBMCs in an in vitro cytokine storm assay from 10-1,000 nM; increases proliferation and activation of tumor-infiltrating T cells and decreases tumor volume in a CT26 murine colon cancer model at 10 mg/kg, p.o.

保存温度:

-20

运输温度:

-20

预期分子量:

360.32344

产品形式:

A solid

有效期:

1460

纯度:

≥95%