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折扣/货期| 货号：22464-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：22464-10 mg | 规格：10 mg | 目录价：￥2050 |
| 货号：22464-25 mg | 规格：25 mg | 目录价：￥4502 |
| 货号：22464-5 mg | 规格：5 mg | 目录价：￥1380 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PD 166866
产品描述:
A potent inhibitor of FGFR1 (IC50 = 52.4 nM; Ki = 45.2 nM); selective for FGFR1 over PDGFR, EGFR, C-SRC, MEK, PKC, insulin receptor tyrosine kinase, and CDK4 (IC50s = >50 μM); inhibits FGFR1 autophosphorylation in NIH3T3 and L6 cells (IC50s = 10.8 and 3.1 nM, respectively); inhibits phosphorylation of MAPK (IC50 = 4.3 and 7.9 nM for the 44- and 42-kDa MAPK isoforms, respectively); reduces FGF- but not EGF- or PDGF-stimulated growth of L6 cells and inhibits microvessel outgrowth from human placental arteries in vitro; inhibits growth of NSCLC cell lines a dose-dependent manner; reduces migration of VL-8 cells at a concentration of 10 μM
保存温度:
-20
运输温度:
-20
预期分子量:
396.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
192705-79-6
分子式:
C20H24N6O3
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