深圳欣博盛生物科技有限公司 a1

PD 180970
货号:30619-1 mg 规格:1 mg 目录价:¥482
货号:30619-10 mg 规格:10 mg 目录价:¥3162
货号:30619-5 mg 规格:5 mg 目录价:¥1715
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PD 180970
产品描述:
A Bcr-Abl inhibitor; inhibits wild-type and mutant forms of Bcr-Abl, as well as the p210 isoform (IC50s = 5-48 nM); selective for Bcr-Abl over bFGFR and PDGFR (IC50s = 934 and 1,430 nM, respectively) but also inhibits Src, LCK, KIT, and EGFR (IC50s = 0.8, 1 phase and apoptosis in K562 cells at 50 nM; inhibits constitutive STAT3 DNA-binding activity in and proliferation of MDA-MB-468 breast cancer cells; inhibits proliferation of imatinib-resistant mutant p210 Bcr-AblY253F Ba/F3 cells
保存温度:
-20
运输温度:
-20
预期分子量:
429.273963
产品形式:
A solid
纯度:
≥98%
CAS号:
287204-45-9
分子式:
C21H15Cl2FN4O
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