货号:AG-CR1-0029-M001 | 规格:1 mg | 目录价:¥240 |
货号:AG-CR1-0029-M005 | 规格:5 mg | 目录价:¥960 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PD 184,352
别名:
2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide; CI-1040
产品描述:
MEK (MAPKK) inhibitor [5]. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo) [1, 2]. Suppresses activation of MAPK but does not block its activity [3]. Antiproliferative [4]. Causes cell-cycle arrest in G1 phase [4]. Tumor suppressor [1, 5]. Apoptosis inducer [6].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
478.7
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
212631-79-3
分子式:
C17H14ClF2IN2O2
溶解度:
Soluble in DMSO.
促销活动
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