深圳欣博盛生物科技有限公司

PepMix Collection Melanoma

Collection of 7 peptide pools derived from scans (overlapping peptides scans, 15mers with 11 aa overlap) through 7 tumor associated antigens (melanoma markers: MAGEA1, MAGEA3, MAGEA4, Melan-A/MART-1, Melanocyte protein Pmel 17 gp100, Tyrosinase, Tyrosinase-related protein 2) of Homo sapiens plus 2 control pools (CEF Pool (extended) and Actin)Amount: 9 peptide pools each containing 15nmol per peptide PepMix™ Collection Melanoma - SpecificationsAmount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)Delivery Format: Freeze-dried in 9 glass vialsApplication(s): T-cell Immunity, Cancer biomarker researchCondition(s)/Topic(s): Cancer, MelanomaStandard Delivery Time: 2-5 daysThis PepMix Collection contains 7 different TAA PepMixes: Human (MAGEA1)Human (MAGEA3)Human (MAGEA4)Human (Melan-A/MART-1)Human (Melanocyte protein Pmel 17 gp100)Human (Tyrosinase),Human (Tyrosinase-related protein 2)and as positive controls:CEF Pool (extended)Human (Actin)Are you interested in your own custom PepMix? Choose your sequence, amount, purity and pool format. We will assist you along the way. Custom PepMix Peptide Pools.PepMix™ Peptide PoolsProtein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)- In-vitro T cell expansion- Dendritic cell pulsing- Immune monitoring- Cellular immune response profiling- T cell epitope identification- Standardization of T cell assaysBenefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)

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JPT Peptide Technologies

Development Grade: each peptide purified to > 70% (HPLC/MS)