深圳欣博盛生物科技有限公司

PepMix VZV (gE)

Glycoprotein Envelope from Varicella-Zoster Virus – HHV3Glycoprotein Envelope (gE) is the most abundant protein on the surface of Varicella-Zoster Virus (VZV) - strain Dumas, also known as human herpesvirus 3 (HHV-3, HHV3). VZV gE or HHV3 gE is highly immunogenic and elicits strong specific IgG production. VZV encodes for several glycoproteins, including glycoprotein I (gI) which forms a heterodimer with gE to allow the virus to be active.PepMix™ Peptide Pool VZV (gE)The VZV gE peptide pool elicits specific T-cells stimulation including cytokine release and expression of specific markers. Thus, specific glycoprotein envelope T-cells can be detected, monitored or isolated and be useful for vaccine immunemonitoring, basic research, and more. PepMix™ VZV gE can be combined with PepMix™ VZV gI (PM-VZV-gI) for further assays. Pool of 153 peptides derived from a peptide scan (15mers with 11 aa overlap) through Envelope protein (Swiss-Prot ID: P09259) of Varicella-Zoster Virus (VZV) - strain Dumas.PepMix™ VZV (gE) - SpecificationsAmount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)Delivery Format: Freeze-dried in glass vialApplication(s): T-cell ImmunityCondition(s)/Topic(s): Chicken Pox, Herpes zoster, Shingles, InfectionStandard Delivery Time: 2-5 daysCustomize your VZV gE poolJPT can accommodate any specific request by preparing custom peptide pools with additional sequences, modifying the sequence design, delivering pools in specific formats (special aliquots, special tubes, plates, ready-to-use tubes...). High quality grades for clinical applications are also available. Contact us for inquiries about the production of custom peptide pools or visit Custom PepMix Peptide Pools.About PepMix™ Peptide PoolsPepMix™ Peptide PoolsProtein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)- In-vitro T cell expansion- Dendritic cell pulsing- Immune monitoring- Cellular immune response profiling- T cell epitope identification- Standardization of T cell assaysBenefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)

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JPT Peptide Technologies

Development Grade: each peptide purified to > 70% (HPLC/MS)