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折扣/货期| 货号：22111-1 mg | 规格：1 mg | 目录价：￥496 |
| 货号：22111-10 mg | 规格：10 mg | 目录价：￥2600 |
| 货号：22111-25 mg | 规格：25 mg | 目录价：￥5842 |
| 货号：22111-5 mg | 规格：5 mg | 目录价：￥1420 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-01247324
产品描述:
An Nav1.8 sodium channel blocker (IC50 = 0.19 μM for human Nav1.8); selective for Nav1.8 over Nav1.1, Nav1.2, Nav1.5, and Nav1.7 channels (IC50s = 13, 12.8, 9, and 19 μM, respectively) as well as ERG potassium channels (IC50 = 30 μM); blocks Nav1.8 channels in a VSP-FRET assay using HEK293 cells (IC50 = 2.6 μM); reduces phase 2 flinching in a rat model of formalin-induced persistent pain at 100 mg/kg; increases latency to lift the inflamed paw and latency to paw withdrawal in rat models of carrageenan-induced thermal hyperalgesia and CFA-induced mechanical hyperalgesia, respectively
保存温度:
-20
运输温度:
-20
预期分子量:
330.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
875051-72-2
分子式:
C13H10Cl3N3O
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