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折扣/货期| 货号：24299-1 mg | 规格：1 mg | 目录价：￥536 |
| 货号：24299-10 mg | 规格：10 mg | 目录价：￥2546 |
| 货号：24299-25 mg | 规格：25 mg | 目录价：￥5668.2 |
| 货号：24299-5 mg | 规格：5 mg | 目录价：￥1407 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-04447943
产品描述:
A brain-permeable PDE inhibitor selective for PDE9A (IC50 = 12 nM) over other PDEs (IC50s = >940 nM); over 1,000-fold more selective for PDE9A over 79 non-PDE targets, with the exception of the melatonin MT3/ML2 receptor (Ki = 3,800 nM); inhibits rat and rhesus monkey PDE9A (Kis = 18.1 and 4.5 nM, respectively); increases neurite outgrowth and the density of synapsin puncta in primary rat hippocampal neurons (0.03 μM); improves scopolamine-induced deficits in episodic memory in rats and increases the time spent exploring the novel object in the NOR test (1 mg/kg); improves spatial memory in the MWM and decreases the distance traveled to the hidden platform (3.2 mg/kg)
保存温度:
-20
运输温度:
-20
预期分子量:
395.5
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1082744-20-4
分子式:
C20H25N7O2
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