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折扣/货期| 货号：24449-10 mg | 规格：10 mg | 目录价：￥2747 |
| 货号：24449-25 mg | 规格：25 mg | 目录价：￥5735 |
| 货号：24449-5 mg | 规格：5 mg | 目录价：￥1447 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-05089771 (tosylate)
产品描述:
An Nav1.7 channel blocker (IC50s = 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively); selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50s = 0.11-25 μM), L-type calcium, and KvLQT and hERG potassium channels (IC50s = ≥10 μM), as well as human and cynomolgus monkey TRPV1 receptors (IC50s = 10 and 20 μM); 1,000-fold selective for half-inactivated over resting Nav1.7 channels; mutation of VSD4 reduces potency by ~100-fold
保存温度:
-20
运输温度:
-20
预期分子量:
500.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1430806-04-4
分子式:
C18H12Cl2FN5O3S2 • C7H8O3S
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