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折扣/货期| 货号：29489-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：29489-10 mg | 规格：10 mg | 目录价：￥2720 |
| 货号：29489-5 mg | 规格：5 mg | 目录价：￥1715 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-05105679
产品描述:
A TRPM8 antagonist (IC50 = 103 nM for inhibition of voltage-activated currents in HEK293 cells expressing the human receptor); >100-fold selective for TRPM8 over a panel of 90 receptors, ion channels, and enzymes; inhibits cold- and WS-12-induced calcium flux in HEK293 cells expressing the human TRPM8 (IC50s = 480 and 181 nM, respectively); reverses cold-induced reductions in bladder capacity in anesthetized guinea pigs when administered as an i.v. infusion at 46.67 μg/kg per minute; decreases the core body temperature in rats at 100 and 300 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
428.455023
产品形式:
A solid
纯度:
≥98%
CAS号:
1398583-31-7
分子式:
C26H21FN2O3
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