| 货号:36856-1 mg | 规格:1 mg | 目录价:¥1206 |
| 货号:36856-10 mg | 规格:10 mg | 目录价:¥10117 |
| 货号:36856-5 mg | 规格:5 mg | 目录价:¥5654.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PF-05221304
别名:
Clesacostat
产品描述:
An inhibitor of ACC1 and ACC2 (IC50s = 12.4 and 8.7 nM, respectively); inhibits de novo lipid synthesis (IC50 = 61 nM) and increases fatty acid oxidation in primary human hepatocytes; reduces the accumulation of triglycerides composed of de novo-derived fatty acids in primary human hepatocytes; reduces hepatic malonyl-CoA production and de novo lipogenesis in rats at 10 and 100 mg/kg; reduces hepatic fibrosis, ALT and AST levels, and hepatic triglyceride accumulation in a rat model of CDAHFD-induced NASH
保存温度:
-20
运输温度:
-20
预期分子量:
502.56176
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1370448-25-1
分子式:
C28H30N4O5
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