官网链接
折扣/货期| 货号：21054-10 mg | 规格：10 mg | 目录价：￥1219 |
| 货号：21054-100 mg | 规格：100 mg | 目录价：￥10278 |
| 货号：21054-250 mg | 规格：250 mg | 目录价：￥16629 |
| 货号：21054-50 mg | 规格：50 mg | 目录价：￥5749 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-06651600
别名:
Ritlecitinib
产品描述:
A covalent JAK3 inhibitor (IC50 = 33.1 nM); selective for JAK3 over JAK1, JAK2, and TYK2 (IC50s = >10,000 for all) and a panel of 304 other kinases at 1 µM; inhibits STAT5, STAT6, and STAT3 phosphorylation induced by IL-2, IL-4, or IL-21, respectively, in isolated human lymphocytes (IC50s = 244, 340, and 350 nM, respectively); inhibits T cell differentiation into Th1 and Th17 in a T cell differentiation assay (IC50s = 30 and 167 nM, respectively); reduces paw swelling in a rat model of adjuvant-induced arthritis at 3, 10, or 30 mg/kg; decreases disease severity in a mouse model of EAE when at 30 or 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
285.3
产品形式:
A solid
纯度:
≥95%
CAS号:
1792180-81-4
分子式:
C15H19N5O
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