深圳欣博盛生物科技有限公司 a1

PGF Antibody / PLGF / Placenta Growth Factor
货号:RQ4653 规格:100 ug 目录价:¥6488.05
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PGF Antibody / PLGF / Placenta Growth Factor
产品描述:
Placental growth factor (PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor (VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors (VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, Direct ELISA
同种型:
Rabbit IgG
免疫原:
Amino acids E37-D60 from the human protein were used as the immunogen for the PGF antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the PGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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