| 货号:41279-1 mg | 规格:1 mg | 目录价:¥415 |
| 货号:41279-10 mg | 规格:10 mg | 目录价:¥3095 |
| 货号:41279-5 mg | 规格:5 mg | 目录价:¥1662 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PHA-408
别名:
PHA-767408
产品描述:
An IKKβ inhibitor (IC50 = 0.04 µM); selective for IKKβ over IKKα, Pim-1, Pim-2, Tie2, TrkA, and p70S6K (IC50s = 0.6-28.4 µM), as well as a panel of 26 kinases (IC50s = >30 µM); inhibits IL-1β-induced PGE2 production in synovial fibroblasts isolated from patients with rheumatoid arthritis (IC50 = ~0.6 µM); reduces serum LPS-induced TNF-α production in rats at 50 mg/kg; inhibits joint swelling and bone destruction in a rat model of streptococcal cell wall-induced arthritis at 10 mg/kg; inhibits LPS- or cigarette smoke-induced BALF neutrophil influx and reduces BALF levels of IL-6, TNF-α, and IL-1β in rats at 15 and 45 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
560.021763
产品形式:
A solid
纯度:
≥98%
CAS号:
503555-55-3
分子式:
C29H27ClFN7O2
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