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折扣/货期| 货号：3151-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：3151-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PHAP I Antibody
别名:
PHAP I Antibody: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1, LANP, Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P,IF
靶标/特异性:
This polyclonal antibody has no cross-reaction to PHAP I2a and PHAP III.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
PHAP I Antibody is DEAE purified.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
PHAP I antibody can be stored at 4˚C up to one year. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PHAP I Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Accession #:
P39687
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