深圳欣博盛生物科技有限公司 a1

Phenoxybenzamine (hydrochloride)
货号:16211-1 g 规格:1 g 目录价:¥657
货号:16211-10 g 规格:10 g 目录价:¥5038
货号:16211-25 g 规格:25 g 目录价:¥6285
货号:16211-5 g 规格:5 g 目录价:¥2854
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Phenoxybenzamine (hydrochloride)
别名:
NSC 37448
产品描述:
An α-AR antagonist; inhibits norepinephrine-induced inositol phosphate formation in HEK293 cells expressing α1-ARs (EC50s = 125.9-316.2 nM), as well as radioligand binding to α2A-, α2B-, and α2C-ARs in CHO cell membranes (Kis = 60, 10, and 60 nM, respectively); decreases norepinephrine-, histamine-, and calcium-induced contractions in isolated rabbit aortic strips from 0.5-5 µM; inhibits proliferation of a variety of cancer cell lines (IC50s = 29.5-99.8 µM); reduces cirazoline-, St-587-, Sgd 101/75-, and B-HT 920-induced increases in diastolic blood pressure in pithed rats; decreases the time to find the platform in the Morris water maze, indicating restored spatial memory, in a rat model of fluid percussion-induced TBI
保存温度:
-20
运输温度:
-20
预期分子量:
303.84
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
63-92-3
分子式:
C18H22ClNO • HCl
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