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折扣/货期| 货号：CDX-P0263-M250 | 规格：250 mg | 目录价：￥546 |
| 货号：CDX-P0263-G001 | 规格：1 g | 目录价：￥896 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Phlorizin
别名:
Floridzin; Phloretin 2'-glucoside; Phloridzosid; Phlorizin; NSC 2833
产品描述:
Phlorizin is a natural product, first isolated from the bark of apple trees, that reduces plasma glucose levels by blocking renal and intestinal glucose absorption through inhibition of SGLT1 and SGLT2. It competitively inhibits (competes with D-glucose) the initial rate of alpha-methyl-D-glucopyranoside (alpha-MDG) uptake in the nM range. Phlorizin has been shown to enhance insulin sensitivity and to have antioxidant properties. Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream. Selective inhibition of SGLT2 is a potential strategy for reducing plasma glucose levels as a treatment for diabetes.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
436.413
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
60-81-1
分子式:
C21H24O10
溶解度:
Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (5mg/ml).
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