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折扣/货期| 货号：7859-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：7859-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PINK1 Antibody
别名:
PINK1 Antibody: BRPK, PARK6BRPK
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P,IF
靶标/特异性:
PINK1 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will only detect the longer isoform. PINK1 antibody will detect the cleaved and uncleaved form of PINK1.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
PINK1 antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
PINK1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PINK1 antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The PTEN-induced putative kinase 1 (PINK1) is a serine/threonine protein kinase that localizes to mitochondria and is thought to protect cells from stress-induced mitochondrial dysfunction (reviewed in 1). PINK1 recruits the E3 ubiquitin ligase Parkin to mitochondria to initiate mitophagy, an autophagic process that clears damaged mitochondria within a cell (2). PINK1 is cleaved by the mitochondrial protease PARL (3). Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease (4).
Accession #:
NP_115785
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