| 货号:F53741-0.1ML | 规格:0.1 ml | 目录价:¥6344 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PINK1 Antibody
产品描述:
PINK1 protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form. [UniProt]
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
WB, IHC, ELISA
同种型:
Mouse IgG1
免疫原:
Recombinant protein was used to produced this PINK1 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
38CT20.8.5
纯化方式:
Ascites
保存温度:
Aliquot the PINK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Ascites
存储溶液:
In ascites with 0.09% sodium azide
产地:
美国
促销活动
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