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折扣/货期| 货号：22440-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：22440-10 mg | 规格：10 mg | 目录价：￥3752 |
| 货号：22440-5 mg | 规格：5 mg | 目录价：￥1997 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PKF118-310
别名:
NSC 67078|Toxoflavin
产品描述:
An inhibitor of the Tcf4-β-catenin protein interaction; disrupts binding of β-catenin to a GST-Tcf4 fusion protein in HCT116 cell lysates (IC50 = 0.8 µM); blocks appearance of the Tcf4 and β-catenin complex bound to DNA in an EMSA assay; reduces levels of the β-catenin regulated proteins c-Myc and cyclin D1 in HCT116 cells; reduces growth of HCT116, HT-29, PC3, and DU145 cancer cells in vitro (IC50s = 170-300 nM); reduces tumor growth and expression of c-Myc, cyclin D1, and Survivin in a HepG2 mouse xenograft model (1 mg/kg twice per week)
保存温度:
-20
运输温度:
-20
预期分子量:
193.2
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
84-82-2
分子式:
C7H7N5O2
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