PLAUR Antibody / uPAR / uPA Receptor-多抗-深圳欣博盛生物科技有限公司

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PLAUR Antibody / uPAR / uPA Receptor

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ6957

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PLAUR Antibody / uPAR / uPA Receptor

产品描述:

PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant human protein (amino acids E128-R167) was used as the immunogen for the PLAUR antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity purified

保存温度:

After reconstitution, the PLAUR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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