深圳欣博盛生物科技有限公司 a1

PLX51107
货号:30742-1 mg 规格:1 mg 目录价:¥1407
货号:30742-5 mg 规格:5 mg 目录价:¥4060
货号:30742-500 µg 规格:500 µg 目录价:¥844
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PLX51107
产品描述:
A BET family protein inhibitor; binds to BD1 in BRD2, BRD3, BRD4, and BRDT (Kds = 1.6, 2.1, 1.7, and 5 nM, respectively), as well as BD2 (Kds = 5.9, 6.2, 6.1, and 120 nM, respectively); binds to bromodomains of CBP and p300 (Kds = ~100 nM for both); inhibits CpG-induced proliferation of primary CLL cells from 0.1-10 µM; inhibits Ba/F3 cell-induced splenomegaly in mice from 0.5-10 mg/kg; reduces tumor volume and increases survival in YUMM3.3 and D4M3.A mouse syngeneic B-RAFV600E mutant melanoma models
保存温度:
-20
运输温度:
-20
预期分子量:
438.47804
产品形式:
A solid
纯度:
≥98%
CAS号:
1627929-55-8
分子式:
C26H22N4O3
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