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折扣/货期| 货号：37324-1 mg | 规格：1 mg | 目录价：￥375.2 |
| 货号：37324-10 mg | 规格：10 mg | 目录价：￥1299.8 |
| 货号：37324-25 mg | 规格：25 mg | 目录价：￥2773.8 |
| 货号：37324-5 mg | 规格：5 mg | 目录价：￥737 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Poseltinib
别名:
HM71224|LY3337641
产品描述:
An irreversible inhibitor of BTK (IC50 = 1.95 nM); selective for BTK over a panel of 85 additional kinases at 2 µM but does inhibit BMX, Tec, and TXK (IC50s = 0.64, 4.57, and 4.62 nM, respectively), as well as EGFR, Blk, and JAK3 (IC50s = 4.96, 13.5, and 14.6 nM, respectively); decreases the levels of CD40, CD69, or CD86 on anti-IgM F(ab’)2-activated primary human B cells (IC50s = 4.2, 4.2, and 7.7 nM, respectively); reduces the differentiation of isolated human CD14+ monocytes into osteoclasts at 1 µM; decreases disease severity and bone erosion in a mouse model of collagen-induced arthritis at 10 or 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
470.52328
产品形式:
A solid
纯度:
≥98%
CAS号:
1353552-97-2
分子式:
C26H26N6O3
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