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折扣/货期| 货号：10008319-10 mg | 规格：10 mg | 目录价：￥295 |
| 货号：10008319-100 mg | 规格：100 mg | 目录价：￥1474 |
| 货号：10008319-1 g | 规格：1 g | 目录价：￥11792 |
| 货号：10008319-500 mg | 规格：500 mg | 目录价：￥6633 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Pranlukast
别名:
ONO-1078|ONO-RS-411
产品描述:
An orally bioavailable CysLT1 receptor antagonist (IC50 = 4.3-7.2 nM); selective for the CysLT1 receptor over the CysLT2 receptor (IC50 = 3,620 nM for the human receptor); inhibits mucus secretion induced by LTD4 in isolated guinea pig trachea (IC50 = 0.3 µM); inhibits TNF-α-induced NF-ĸB p65 nuclear localization in U937 and Jurkat cells at 10 and 100 µM; inhibits bronchoconstriction induced by LTC4, LTD4, and LTE4, but not LTB4, in guinea pigs (ID50s = 0.8, 1, 0.7, and >500 µg/kg, respectively); reduces cortical infarct volume by 81.6% and decreases neuronal death in the cortex, hippocampus, and striatum in a rat model of MCAO-induced ischemia at 0.03 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
481.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
103177-37-3
分子式:
C27H23N5O4
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