| 货号:15023-100 mg | 规格:100 mg | 目录价:¥844 |
| 货号:15023-250 mg | 规格:250 mg | 目录价:¥1715 |
| 货号:15023-50 mg | 规格:50 mg | 目录价:¥482 |
| 货号:15023-500 mg | 规格:500 mg | 目录价:¥3162 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Prazosin (hydrochloride)
别名:
CP 12,299-1|NSC 292810
产品描述:
An α1-AR antagonist; selectively binds to α1-ARs (Kis = 0.2, 0.25, and 0.32 nM for the human recombinant α1A-, α1B-, and α1D-ARs, respectively), over α2-ARs (Kis = 340 and 3.7 nM in α2A-AR-expressing HT-29 cells and α2B-AR-expressing NG108 cells, respectively); binds to MT3 in hamster brain membranes (IC50 = 7.8 nM); inhibits peripheral and central postsynaptic α1-ARs (IC50s = 0.2 and 1.7 nM in isolated dog aorta and rat brain, respectively); decreases diastolic blood pressure in normal, renal hypertensive, and spontaneously hypertensive rats at 1 mg/kg; increases the number of entries and percentage of time spent in the open arms of the elevated plus maze in alcohol-consuming rats and also reduces alcohol intake and alcohol-seeking behavior in alcohol-preferring rats at 1.5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
383.44
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
19237-84-4
分子式:
C19H21N5O4 • HCl
促销活动
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