官网链接
折扣/货期| 货号：25835-1 mg | 规格：1 mg | 目录价：￥3618 |
| 货号：25835-5 mg | 规格：5 mg | 目录价：￥10841 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
proTAME
别名:
Pro-N-4-tosyl-L-arginine methyl ester
产品描述:
A cell-permeable prodrug form of TAME; is converted to TAME by intracellular esterases; blocks association of APC/C with the activator CDH1 and inhibits degradation of APC/C substrates in HeLa cells at 12 μM; induces mitotic arrest in metaphase followed by cell death in synchronized HeLa H2B-GFP cells at 12 μM; increases mitotic duration in asynchronous HeLa H2B-GFP at 4 μM, an effect that is enhanced by knockdown of the APC/C co-activator CDC20; decreases the viability of several laboratory and primary patient-derived human MM cell lines (IC50s = 2.8-20.3 μM); increases apoptosis in RPMI-8226, LP-1, NCI-H929, and U266 MM cells at 12 μM
保存温度:
-20
运输温度:
-20
预期分子量:
726.75128
产品形式:
A 10 mg/ml solution in methyl acetate
纯度:
≥90%
CAS号:
1362911-19-0
分子式:
C34H38N4O12S
促销活动
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