PSEN1 Antibody / Presenilin 1-多抗-深圳欣博盛生物科技有限公司

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PSEN1 Antibody / Presenilin 1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ6791

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PSEN1 Antibody / Presenilin 1

产品描述:

Presenilin-1 (PS-1) is a presenilin protein that in humans is encoded by the PSEN1 gene. Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IF, FACS, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant human protein (amino acids M1-K76) was used as the immunogen for the PSEN1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity purified

保存温度:

After reconstitution, the PSEN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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