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折扣/货期| 货号：60-913 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PTPN1 Antibody
别名:
Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTPN1, PTP1B
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The protein encoded by this gene is the founding member of
the protein tyrosine phosphatase (PTP) family, which was isolated
and identified based on its enzymatic activity and amino acid
sequence. PTPs catalyze the hydrolysis of the phosphate monoesters
specifically on tyrosine residues. Members of the PTP family share
a highly conserved catalytic motif, which is essential for the
catalytic activity. PTPs are known to be signaling molecules that
regulate a variety of cellular processes including cell growth,
differentiation, mitotic cycle, and oncogenic transformation. This
PTP has been shown to act as a negative regulator of insulin
signaling by dephosphorylating the phosphotryosine residues of
insulin receptor kinase. This PTP was also reported to
dephosphorylate epidermal growth factor receptor kinase, as well as
JAK2 and TYK2 kinases, which implicated the role of this PTP in
cell growth control, and cell response to interferon stimulation.
Accession #:
P18031
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