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折扣/货期| 货号：3043-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：3043-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PUMA Antibody
别名:
PUMA Antibody: JFY1, PUMA, JFY-1, Bcl-2-binding component 3
反应种属:
Human,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P,IF
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
PUMA Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
PUMA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PUMA Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
PUMA Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53 (1). The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta (2). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Accession #:
NP_055232
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