深圳欣博盛生物科技有限公司 a1

PYR41
货号:15226-1 mg 规格:1 mg 目录价:¥389
货号:15226-10 mg 规格:10 mg 目录价:¥1327
货号:15226-5 mg 规格:5 mg 目录价:¥764
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PYR41
产品描述:
An irreversible inhibitor of ubiquitin-activating enzyme (E1; IC50 = 50 = 6.4 µM); selective for E1 over E2 but does inhibit autoubiquitination of the HECT domain E3 Nedd4 at 50 µM; inhibits proteasome-dependent and -independent ubiquitination and protein degradation at 50 µM; preferentially induces apoptosis of E1A-transformed RPE cells expressing wild-type p53 over non-transformed RPE cells at 1-20 µM; also increases net cellular sumoylation and irreversibly cross-links proteins such as JAK2 and Bcr-Abl
保存温度:
-20
运输温度:
-20
预期分子量:
371.3
产品形式:
A crystalline solid
纯度:
≥95% (mixture of cis and trans isomers)
CAS号:
418805-02-4
分子式:
C17H13N3O7
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