深圳欣博盛生物科技有限公司 a1

PZ-2891
货号:37309-10 mg 规格:10 mg 目录价:¥1809
货号:37309-25 mg 规格:25 mg 目录价:¥3578
货号:37309-5 mg 规格:5 mg 目录价:¥1206
货号:37309-50 mg 规格:50 mg 目录价:¥6553
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PZ-2891
别名:
Pantazine 2891
产品描述:
A modulator of pantothenate kinase; selectively inhibits PanK1β, PanK2, and PanK3 (IC50s = 40.2, 0.7, and 1.3 nM, respectively) in the absence of acetyl-CoA over 468 other kinases and a panel of 72 receptors and ion channels at 10 µM; reverses acetyl-CoA-induced inhibition of PanK3 in a cell-free assay at 2.5 µM; increases intracellular CoA levels in wild-type PanK3-expressing, but not PanK3E138A-expressing, HEK293T cells; increases survival in a mouse model of neuronal CoA deficiency induced by brain knockout of Pank1 and Pank2; prevents infection of mosquitoes (A. stephensi) by P. falciparum
保存温度:
-20
运输温度:
-20
预期分子量:
349.42972
产品形式:
A solid
纯度:
≥98%
CAS号:
2170608-82-7
分子式:
C20H23N5O
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