(R)-Roscovitine-抑制剂-深圳欣博盛生物科技有限公司

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(R)-Roscovitine

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-0006-M001	规格：1 mg	目录价：￥360
货号：AG-CR1-0006-M005	规格：5 mg	目录价：￥720
货号：AG-CR1-0006-M050	规格：50 mg	目录价：￥2400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

(R)-Roscovitine

别名:

6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine

产品描述:

Potent and selective inhibitor of CDKs [1, 2, 4, 16]. More potent than olomoucine [3]. Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) [2], CDK2 (IC50 = 700 nM) [4] and CDK5/p35 (IC50 = 160 nM) [4,5]. Inhibits M phase promoting factor (MPF) kinase activity [2]. Arrests human fibroblasts in G1 phase [6]. Antitumor compound [8]. Activates the mitogen-activated protein kinase pathway [9]. Targets both the p53 and NF-kappaB pathways[10]. Has effects on calcium channel gating [12, 17, 18]. Prevents DNA damage-induced cyclin A1 upregulation [13]. Apoptosis inducer [11, 15, 20]. As CYC202 in phase I clinical trials [14]. Reviews [3, 7, 19].

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

354.5

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)