深圳欣博盛生物科技有限公司 a1

(R)-STU104
货号:45375-1 mg 规格:1 mg 目录价:¥657
货号:45375-10 mg 规格:10 mg 目录价:¥4275
货号:45375-25 mg 规格:25 mg 目录价:¥6566
货号:45375-5 mg 规格:5 mg 目录价:¥2305
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
(R)-STU104
产品描述:
An inhibitor of the TAK1-MKK3 protein-protein interaction; binds MKK3 (KD = 71 nM), inhibits the phosphorylation of MKK3 in RAW 264.7 macrophages (IC50 = 4 µM), and disrupts the interaction between MKK3 and TAK1 in the same cells; reduces TNF-α levels (IC50 = 0.58 µM) and p38 and eIF4E phosphorylation in LPS-stimulated RAW 264.7 macrophages; increases body weight and colon length and reduces serum levels of TNF-α, IL-1β, IL-6, and IL-23 in mouse model of ulcerative colitis induced by DSS; increases the survival rate in an IL-10-/- knockout mouse model of chronic ulcerative colitis
保存温度:
-20
运输温度:
-20
预期分子量:
298.338
产品形式:
A solid
纯度:
≥98%
CAS号:
2767124-77-4
分子式:
C18H18O4
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询