Rad17 Antibody-多抗-深圳欣博盛生物科技有限公司

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Rad17 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ5917

规格：100 ug

目录价：￥6488

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Rad17 Antibody

产品描述:

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.

反应种属:

Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P, FACS, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant mouse protein (amino acids M1-Q267) was used as the immunogen for the Rad17 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Affinity purified

保存温度:

After reconstitution, the Rad17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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