Recombinant Human ApoE2-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human ApoE2

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：350-12-100UG	规格：100 ug	目录价：￥1207
货号：350-12-01M	规格：2 x 500 ug	目录价：￥6026
货号：350-12-500UG	规格：500 ug	目录价：￥2941

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human ApoE2

别名:

Apolipoprotein E2

产品描述:

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in the liver and brain, and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. Its interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. E2 allele carriers had significantly lower levels of total cholesterol, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, as well as increased ApoE levels. Recombinant Human ApoE2 is a 34.3 kDa protein containing 300 amino acid residues.

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Standard

产地:

美国

生产商:

PeproTech