Recombinant Human C1 Inhibitor-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

首页产品中心细胞因子、趋化因子与生长因子

Recombinant Human C1 Inhibitor

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：130-20-1MG	规格：1 mg	目录价：￥14218
货号：130-20-200UG	规格：200 ug	目录价：￥2956
货号：130-20-500UG	规格：500 ug	目录价：￥9223
货号：130-20-50UG	规格：50 ug	目录价：￥1213

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human C1 Inhibitor

别名:

Plasma protease C1 inhibitor, C1inh, C1 Esterase Protein, C1-inhibiting factor, Serpin G1

产品描述:

C1 inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 inhibitor is a protease inhibitor that functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1 inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1 inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1 inhibitor can be used to treat HAE and certain other conditions. Recombinant Human C1 Inhibitor is a highly glycosylated glycoprotein containing 478 amino acid residues (52.8kDa), corresponding to amino acids 23-500 of the C1 inhibitor precursor, and is fully functional in its ability to inhibit the C1 complex. Glycosylated C1 Inhibitor migrates at an apparent molecular weight of approximately 80-90 kDa by SDS PAGE analysis under reducing conditions.

宿主来源:

CHO cells

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech