Recombinant Human FGFR1a (IIIc) Fc-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human FGFR1a (IIIc) Fc

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：160-02-100UG	规格：100 ug	目录价：￥6005
货号：160-02-10UG	规格：10 ug	目录价：￥1213
货号：160-02-1MG	规格：1 mg	目录价：￥26653
货号：160-02-250UG	规格：250 ug	目录价：￥11632
货号：160-02-500UG	规格：500 ug	目录价：￥17283
货号：160-02-50UG	规格：50 ug	目录价：￥3018

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human FGFR1a (IIIc) Fc

别名:

Fibroblast Growth Factor Receptor 1 alpha, BFGFR

产品描述:

The FGF family plays a central role during prenatal development and postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. The FGF ligands bind to a family of type I transmembrane tyrosine kinase receptors, which leads to dimerization and activation by sequential autophosphorylation of specific tyrosine residues. Four genes encoding structurally related FGF receptors (FGFR-1 to -4) are known. Alternative splicing of the mRNAs generates numerous forms of FGFR-1 to -3. Alternate forms of FGF receptors can exhibit different specificities with respect to ligand binding. For example, the form designated as FGFR1a (IIc) interacts predominantly with FGF-acidic (FGF1) and FGF-basic (FGF2). A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as thebeta isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). Recombinant Human FGFR1a (IIIc) is a 65.2 kDa protein containing 586 amino acids. Under reducing conditions, FGFR1a migrates between 100-110 kDa on SDS-PAGE gel.

宿主来源:

CHO cells

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech