| 货号:310-09B-15UG | 规格:15 ug | 目录价:¥2941 |
| 货号:310-09B-3UG | 规格:3 ug | 目录价:¥1207 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human LIGHT
别名:
TNFSF14, HVEM-L
产品描述:
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to activate NF-kappaB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. The human LIGHT gene encodes for a 240 amino acid type II transmembrane protein containing a 37 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 182 amino acid extracellular domain. Recombinant Human LIGHT has a calculated mass of 19.3 kDa, containing 177 amino acid residues. Due to glycosylation, LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions. *Human LIGHT(Catalog Number 310-09B) has replaced Human LIGHT(Catalog Number 310-09)
宿主来源:
Hi-5 Insect cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Standard
产地:
美国
生产商:
PeproTech
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