| 货号:310-28-100UG | 规格:100 ug | 目录价:¥22960 |
| 货号:310-28-10UG | 规格:10 ug | 目录价:¥2941 |
| 货号:310-28-1MG | 规格:1 mg | 目录价:¥91944 |
| 货号:310-28-250UG | 规格:250 ug | 目录价:¥40148 |
| 货号:310-28-2UG | 规格:2 ug | 目录价:¥1207 |
| 货号:310-28-500UG | 规格:500 ug | 目录价:¥59648 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human sOX40 Ligand
别名:
TNFSF4, OX40L, Gp34, CD252
产品描述:
OX40L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. OX40/OX40L signaling plays an important role in immuno-regulatory communication, enabling the immune system to distinguish between "friend vs. foe" during activation; a mechanism typically termed immuno-tolerance. Recombinant OX40L is a glycosylated 133 amino acid protein corresponding to the extracellular TNF homologous domain of the full length transmembrane protein. It migrates with an apparent molecular mass of 15.5-25.0 kDa on SDS-PAGE.
宿主来源:
Hi-5 Insect cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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