Recombinant Human Thrombomodulin-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human Thrombomodulin

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：100-58-100UG	规格：100 ug	目录价：￥17209
货号：100-58-10UG	规格：10 ug	目录价：￥2941
货号：100-58-1MG	规格：1 mg	目录价：￥68950
货号：100-58-250UG	规格：250 ug	目录价：￥30121
货号：100-58-2UG	规格：2 ug	目录价：￥1207
货号：100-58-500UG	规格：500 ug	目录价：￥44742

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human Thrombomodulin

别名:

CD141, BDCA-3, THBD, TM

产品描述:

Thrombomodulin (TM, CD141, THBD) is an endothelial cell-expressed, transmembrane glycoprotein that can form a complex with the coagulation factor, thrombin. The thrombomodulin/thrombin complex converts protein C to its activated form, protein Ca, which in turn proteolytically cleaves and deactivates factor Va and factor VIIIa, two essential components of the coagulation mechanism. This inactivation reduces the generation of additional thrombin, and thereby effectively prevents continued coagulation. Reduced levels of thrombomodulin can correlate with the pathogenesis of certain cardiovascular diseases, such as atherosclerosis and thrombosis. However, the serum levels of the truncated circulating form of thrombomodulin are typically elevated during inflammation and in the presence of various inflammatory-related diseases. The thrombomodulin protein contains 575 amino acids, including an 18 a.a. signal sequence, a 497 a.a. extracellular domain, a 24 a.a. transmembrane sequence, and a 36 a.a. cytoplasmic region. Recombinant Human Thrombomodulin is a 51.4 kDa, 491-amino-acid length glycoprotein containing the extracellular domain of thrombomodulin.

宿主来源:

HEK293 cells

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech