| 货号:300-62-100UG | 规格:100 ug | 目录价:¥22960 |
| 货号:300-62-10UG | 规格:10 ug | 目录价:¥2941 |
| 货号:300-62-1MG | 规格:1 mg | 目录价:¥91944 |
| 货号:300-62-250UG | 规格:250 ug | 目录价:¥40148 |
| 货号:300-62-2UG | 规格:2 ug | 目录价:¥1207 |
| 货号:300-62-500UG | 规格:500 ug | 目录价:¥59648 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human TSLP
别名:
Thymic Stromal Lymphopoietin
产品描述:
TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL-7, and binds with the heterodimeric receptor complex consisting of the IL-7R alpha-chain (IL-7Ralpha) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibits apoptosis and stimulates growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes, and activates CD11c(+) dendritic cells (DCs). TSLP-activated DCs have been shown to prime naive T cells to produce the proallergic cytokines (IL-4, IL-5, IL-13, TNF-alpha) while down-regulating IL-10 and IFN-gamma, suggesting a role in initiating allergic inflammation. Recombinant Human TSLP is a 15.0 kDa protein consisting of 132 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
促销活动
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