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折扣/货期| 货号：450-44-100UG | 规格：100 ug | 目录价：￥22960 |
| 货号：450-44-10UG | 规格：10 ug | 目录价：￥2941 |
| 货号：450-44-1MG | 规格：1 mg | 目录价：￥91944 |
| 货号：450-44-250UG | 规格：250 ug | 目录价：￥40148 |
| 货号：450-44-2UG | 规格：2 ug | 目录价：￥1207 |
| 货号：450-44-500UG | 规格：500 ug | 目录价：￥59648 |
| 货号：450-44-50UG | 规格：50 ug | 目录价：￥13761 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Murine GDNF
别名:
Glial-Derived Neurotrophic Factor, ATF-1
产品描述:
GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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