Recombinant Murine GDNF-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Murine GDNF

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：450-44-100UG	规格：100 ug	目录价：￥22960
货号：450-44-10UG	规格：10 ug	目录价：￥2941
货号：450-44-1MG	规格：1 mg	目录价：￥91944
货号：450-44-250UG	规格：250 ug	目录价：￥40148
货号：450-44-2UG	规格：2 ug	目录价：￥1207
货号：450-44-500UG	规格：500 ug	目录价：￥59648
货号：450-44-50UG	规格：50 ug	目录价：￥13761

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Murine GDNF

别名:

Glial-Derived Neurotrophic Factor, ATF-1

产品描述:

GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech